The introduction in 1966 of radioisotopic methods measuring gastric emptying has led to more accurate measurement of gastric emptying than the old barium contrast meal and tube recovery, it is now possible to simultaneously measure gastric emptying of both liquid and solid components of normal meals without an invasive technique.
When a pharmaceutical manufacturer concludes, on the basis of early clinical trials of a basic new agent, that a new drug application is likely to be submitted, a proposed development plan accompanied by a summary of existing data, would be submitted to the a review of this submission, the fda, and its advisory committee where.
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